Physical Activity and Prevention of Cognitive Decline:

Evidence From Randomised Controlled Trials

Mild cognitive impairment (MCI) is a common problem that  people can experience when at high risk of developing dementia. Although treatments for MCI are currently unavailable, preliminary evidence has identified potential neuro-protective effects of physical activity, which may lead to improved outcomes.

Three recently published randomized control studies (RCT)'s have investigated the effect of high intensity and moderate intensity PA upon cognition in older adults with MCI.

One RCT in the USA investigated the effect of a 6 month, high-intensity aerobic exercise intervention to improve cognitive function in 29 participants with MCI. Participants in the exercise group trained at a target heart rate of 75–85% heart rate reserve for 45–60 min a day on 4 days of the week. Following aerobic training the exercise group improved in aspects of executive cognitive function. Greater effects were reported in women than men and these effects were associated with reduced insulin resistance and the cortisol level.

Posted: 01/03/2012; Age and Ageing. 2012;41(1):5-8. © 2012 Oxford University Press

Bottom line: Exercise will keep the cobwebs away !